14.7 Ophiostoma (Ceratocystis) novo-ulmi (Dutch Elm disease or DED) (Ascomycota)

Ophiostoma novo-ulmi destroyed most (estimated 25 million) elm trees in the UK, and was responsible for similarly devastating disease epidemics around the world throughout the 20th century. The story illustrates a number of features:

  • disease vectors;
  • geographic isolation, and the creation of ‘new’ diseases when geographical barriers are beached by accidental introductions through intercontinental trade and commerce; and
  • the importance of ‘amenity’ plants.

This tree disease first came to notice in Holland in 1918 and 1919. Elms died soon after first showing symptoms and mature trees were lost in large numbers. It came to be called Dutch Elm Disease because its true cause was established in the 1920s by Dutch scientists. They found it was caused by a fungus first called Ceratocystis. Today we know the fungus as Ophiostoma and recognise three species: O. ulmi, which caused the infection in Europe in 1910 and which reached North America on imported timber in 1928, O. himal-ulmi, found naturally in the western Himalaya, and the most virulent O. novo-ulmi, which was first described in Europe and North America in the 1940s and was responsible for devastating infections of elms in both regions from the late 1960s onwards. O. novo-ulmi could be a hybrid between O. ulmi and O. himal-ulmi. O. ulmi seems to have been brought to Europe accidentally from the Dutch East Indies in Southeast Asia during the late nineteenth century.

Symptoms of Dutch elm disease are symptoms of lack of water and nutrients; described as wilting. Leaves first droop and then turn yellow. In a few days to weeks, the leaves are brown and dead, then larger branches begin to die and most trees are completely dead within two years. The reason for this progression is that the plant reacts to the fungus by plugging its own xylem tissue with gum and tyloses (bubble-like plugs in the xylem cavity formed when adjacent parenchyma cells grow into the conducting cells of the xylem) in a vain attempt to stop the spread of the fungus. As more and more channels are plugged the diseased tree is starved of nutrients and water. When the tree dies the fungus grows saprotrophically on the wood that remains.

But there is more than a fungus involved. Left to itself, the fungus has difficulty passing from tree to tree. In this case, what turns a disease into a raging epidemic is a relationship between the fungus and several species of elm bark beetles. Adult females of these insects lay eggs in recently dead elms. Their eggs hatch and young larvae tunnel into the inner bark and outer wood to feed on it. If the tree has been killed by Dutch elm disease, the fungus sporulates in the beetle tunnels so the adult beetles that emerge are covered with fungus spores. These are transported to the first tender, young, healthy elm twigs that the young beetles bite into. Elm bark beetles, therefore (Scolytus multistriatus in Europe) are vectors of Dutch elm disease. Indeed, the fungal pathogen makes the host trees attract insect vectors, thereby manipulating its host tree to enhance their appeal to foraging beetles (McLeod et al., 2005).

In North America, O. novo-ulmi relies on both the (accidentally introduced) European elm bark beetle, S. multistriatus, and the native elm bark beetle, Hylurgopinus rufipes, for transport to new host elms (H. rufipes can withstand colder winter temperatures and is the primary vector of Dutch elm disease across the North American prairies). Chinese and Siberian elms are highly resistant to the disease, but those native to Europe and North America are not. So the next step in the story is that Dutch elm disease was first found in North America in 1930 in Cincinnati, Ohio.

The evidence indicates that it was introduced on elm logs from Europe landed at ports on the US eastern seaboard. The American elm had become an important amenity tree throughout the continent, being planted in urban sites to such an extent that it’s no exaggeration to describe the plantings as urban forests. But by 1950 the disease was spreading through seventeen states (and into south-eastern Canada). Today, Dutch Elm disease occurs wherever American elms grow in North America. Countless millions of trees have been killed, with a corresponding multi-billion dollar cost of removing and disposing of them and replacing the trees that were lost with new plantings. But the story has yet another twist.

In May 1963 a shipment of American elm logs was landed in the United Kingdom. The logs were infested with both elm bark beetles and Ophiostoma, and in the course of the next few years twenty-five million elm trees died in Britain.

There are hopes for biological control (biocontrol) of DED (Scheffer, Voeten & Guries, 2008) and other fungal pathogens (Massart & Jijakli, 2007). In the DED disease syndrome there are three potential targets, because the biological control might depend on:

  • developing resistant varieties of elm or techniques to induce resistance to disease-causing fungi in susceptible elm;
  • organisms (bacteria or fungi) to compete with Ophiostoma;
  • hyperparasites (that is, parasites of the parasites) of either Ophiostoma or the elm bark beetle;
  • or processes that prevent successful breeding of the beetles.

There is no cure yet, so the key to control of Dutch elm disease is sanitation. Dead, dying, or weak elm wood must be destroyed to eradicate both fungus and beetle. It goes beyond the aerial parts of the tree, though. The roots of adjacent elms tend to fuse together over time, resulting in a shared root system between several trees. This type of root grafting can occur between elms within 50 feet of one another. When a single elm tree in such a group becomes infected, the fungus can move down the diseased tree into the roots and then into the next healthy tree through root grafts. The sanitation processes must include disruption of these root grafts by digging a trench two feet deep along a line around the tree and beyond the longest branches of the diseased tree.

Resources Box

More information about plant pathogens

More information about plant pathogens can be found in the British Society of Plant Pathology’s Pathogen profiles, which are a regular feature in the journal Molecular Plant Pathology and BSPPWeb providing brief overviews of the latest research on particular pathogens.

Profile summaries are available at http://www.bspp.org.uk/ [go to <Publications> and then click on <Molecular Pl. Pathology>]
Full articles can be downloaded from the Blackwell Molecular Plant Pathology web site [http://www.blackwellpublishing.com/journal.asp?ref=1464-6722&site=1]

We would also strongly recommend a visit to the teaching materials on the website maintained by the Department of Plant Pathology of the University of Wisconsin-Madison, USA at this URL:

http://www.plantpath.wisc.edu/PDDCEducation/EducationIndex.htm

Updated December 17, 2016